Applying bioethical principles for directing investment in precision medicine. (March 2020)

• Record Type: Journal Article
• Authors: Finall, Alison; Jones, Kerina
• Is Part Of: Clinical ethics. Volume 15:Number 1(2020)
• Page Start: 23
• Page End: 28
• Publication Date: 2020-03
• Subjects: Bioethics and medical ethics -- genome mapping and sequencing -- resource allocation -- healthcare economics -- genetic counselling -- genetics and genomics; Medical ethics -- Periodicals; 174.205
• DOI: 10.1177/1477750919897380
• Languages: English
• ISSNs: 1477-7509

Abstract

The concept of precision medicine aims to tailor treatment based on data unique to the patient. An example is the use of genetic data from malignant tumours to select the most appropriate oncological treatment. The competing interests of utilitarianism and egoism create dilemmas for decisions regarding investment in precision medicine. The need to balance the perceived rights and needs of individuals against those of society as a whole is an on-going challenge in the distribution of limited health service resources. There is need for proper planning, organisation and investment into precision medicine to cope with the consequences of both direct-to-consumer and healthcare-directed genetic testing for genetic counselling, therapeutics and diagnostic networks. Consideration needs to be given to providing adequate time and training to allow for meaningful shared decision-making with patients and there is a strong case in support of a hub-and-spoke model to provide rapid, solid tumour genetic mutational analysis to prevent patients missing out on beneficial treatments.