Abstract : In article number 1902433, Xiaolin Huang, Yonghua Xiong, and co‐authors report the facile synthesis of magnetic–plasmonic nanoassemblies (MPNAs) which exhibit a typical core–shell structure, wherein oleylamine‐coated gold nanoparticles (OA‐AuNPs) preferentially aggregate and form a plasmonic core and oleic acid‐coated iron oxide nanoparticles (OC‐IONPs) assemble a magnetic shell. The resultant MPNAs hold the highly retained magnetic–plasmonic activities for the separation and simultaneous optical sensing of target compounds in complex biological samples.