Early repolarization pattern in an ethnically diverse population: Increased risk in Hispanics. Issue 1 (22nd December 2019)
- Record Type:
- Journal Article
- Title:
- Early repolarization pattern in an ethnically diverse population: Increased risk in Hispanics. Issue 1 (22nd December 2019)
- Main Title:
- Early repolarization pattern in an ethnically diverse population: Increased risk in Hispanics
- Authors:
- Leiderman, Ephraim
Kargoli, Faraj
Shulman, Eric
Aagaard, Philip
Hoch, Ethan
Zaremski, Lynn
Di Biase, Luigi
Kim, Soo G.
Gross, Jay N.
Ferrick, Kevin J.
Fisher, John
Krumerman, Andrew - Abstract:
- Abstract: Background: Early repolarization (ER) pattern on ECG is associated with an increased mortality in Caucasians. This study analyzed the association between ER pattern and all‐cause mortality in a population of multiple ethnicities. Methods: A total of 20 000 individuals were randomly selected and their ECGs were analyzed for ER pattern using the 2015 consensus: end‐QRS notching or slurring with a J‐point ( Jp ) ≥0.1 mV in contiguous inferior or lateral leads. Exclusion criteria were age <18, QRS duration of ≥120 ms, and acute myocardial infarction. Kaplan‐Meier survival curves were used to assess crude survival, and multivariable logistic regression models were used to determine predictors of all‐cause mortality. Results: A total of 17 901 patients with a mean age of 53 met inclusion criteria. Individuals were 62% female, 14% White, 37% Black, 40% Hispanic, and 9% other. Median follow‐up time was 6.4 years. ER pattern was noted in 995 (5.6%) patients. Jp ≥2 mm was noted in 282 (1.6%) patients. In those with ER pattern and Jp ≥1 mm, there was no difference in mortality when compared to individuals without Jp elevation (odds ratio [OR]: 0.962, 95% confidence of interval [CI]: 0.819‐1.131). Patients with Jp ≥2 mm had a significantly increased all‐cause mortality (OR: 1.333, 95% CI: 1.009‐1.742). This increased mortality was also significant in Hispanic patients with Jp ≥2 mm (OR: 1.584, 95% CI: 1.003‐2.502). Conclusion: ER pattern with Jp ≥2 mm is associated withAbstract: Background: Early repolarization (ER) pattern on ECG is associated with an increased mortality in Caucasians. This study analyzed the association between ER pattern and all‐cause mortality in a population of multiple ethnicities. Methods: A total of 20 000 individuals were randomly selected and their ECGs were analyzed for ER pattern using the 2015 consensus: end‐QRS notching or slurring with a J‐point ( Jp ) ≥0.1 mV in contiguous inferior or lateral leads. Exclusion criteria were age <18, QRS duration of ≥120 ms, and acute myocardial infarction. Kaplan‐Meier survival curves were used to assess crude survival, and multivariable logistic regression models were used to determine predictors of all‐cause mortality. Results: A total of 17 901 patients with a mean age of 53 met inclusion criteria. Individuals were 62% female, 14% White, 37% Black, 40% Hispanic, and 9% other. Median follow‐up time was 6.4 years. ER pattern was noted in 995 (5.6%) patients. Jp ≥2 mm was noted in 282 (1.6%) patients. In those with ER pattern and Jp ≥1 mm, there was no difference in mortality when compared to individuals without Jp elevation (odds ratio [OR]: 0.962, 95% confidence of interval [CI]: 0.819‐1.131). Patients with Jp ≥2 mm had a significantly increased all‐cause mortality (OR: 1.333, 95% CI: 1.009‐1.742). This increased mortality was also significant in Hispanic patients with Jp ≥2 mm (OR: 1.584, 95% CI: 1.003‐2.502). Conclusion: ER pattern with Jp ≥2 mm is associated with increased mortality in a multiethnic population, apparently driven by an increased risk in Hispanics. … (more)
- Is Part Of:
- Pacing and clinical electrophysiology. Volume 43:Issue 1(2020)
- Journal:
- Pacing and clinical electrophysiology
- Issue:
- Volume 43:Issue 1(2020)
- Issue Display:
- Volume 43, Issue 1 (2020)
- Year:
- 2020
- Volume:
- 43
- Issue:
- 1
- Issue Sort Value:
- 2020-0043-0001-0000
- Page Start:
- 30
- Page End:
- 36
- Publication Date:
- 2019-12-22
- Subjects:
- early repolarization -- ethnicity -- Hispanic -- J‐point
Cardiac pacing -- Periodicals
Electrophysiology -- Periodicals
617.4120645 - Journal URLs:
- http://onlinelibrary.wiley.com/journal/10.1111/(ISSN)1540-8159 ↗
http://www.blackwell-synergy.com/rd.asp?goto=journal&code=pace ↗
http://www.futuraco.com/journalsf.htm ↗
http://onlinelibrary.wiley.com/ ↗
http://firstsearch.oclc.org ↗
http://firstsearch.oclc.org/journal=0147-8389;screen=info;ECOIP ↗ - DOI:
- 10.1111/pace.13827 ↗
- Languages:
- English
- ISSNs:
- 0147-8389
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 6328.210000
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