Association between the neutrophil‐to‐lymphocyte ratio and intravesical prostatic protrusion in men with benign prostatic hyperplasia. Issue 1 (15th September 2019)

• Record Type: Journal Article
• Authors: Chung, Mun Su; Yang, Yun Jung; Lee, Seung Hwan; Yoon, Byung Il
• Is Part Of: LUTS. Volume 12:Issue 1(2020)
• Page Start: 62
• Page End: 67
• Publication Date: 2019-09-15
• Subjects: inflammation -- intravesical protrusion -- neutrophil‐to‐lymphocyte ratio -- prostate; Urology -- Periodicals; Urologic Diseases -- Periodicals; Urinary Tract Physiological Phenomena -- Periodicals; 616.62
• DOI: 10.1111/luts.12287
• Languages: English
• ISSNs: 1757-5664

Abstract

Abstract: Objective: To analyze the association between neutrophil‐to‐lymphocyte ratio (NLR) and intravesical prostatic protrusion (IPP) in men with benign prostatic hyperplasia. Methods: Two hundred and fifty men aged >50 years who presented with lower urinary tract symptoms at our institution between 2014 and 2018 were analyzed. Pearson's method was used for analysis of the correlation between NLR and IPP. Multivariate logistic regression analysis was used to identify predictors of IPP. Further analysis according to total prostate volume (TPV) was performed. Results: The NLR correlated positively with IPP (Pearson's r = 0.459, P < 0.001) and was an independent predictor of IPP ≥10 mm (odds ratio, 2.95; 95% confidence interval, 1.59–5.47; P = 0.0006). Among the 142 men with prostates <40 cm 3, mean NLR was 2.50 ± 0.71 in those with IPP ≥10 mm and 1.71 ± 0.57 in those with IPP < 10 mm ( P < 0.001). The NLR differed significantly between those with a prostate <40 cm 3 and IPP ≥10 mm and those with a larger prostate and IPP < 10 mm (2.50 ± 0.71 vs 2.07 ± 0.77, respectively; P = 0.020). Conclusions: NLR can be used as a surrogate marker for presence of IPP. Its clinical value would be especially important in men with a small prostate gland but high IPP. The NLR seemed to be more strongly correlated with IPP than with TPV.