Bacterial translocation in acute pancreatitis. (2nd November 2019)

• Record Type: Journal Article
• Authors: Liu, Jinbo; Huang, Lin; Luo, Ming; Xia, Xianming
• Is Part Of: Critical reviews in microbiology. Volume 45:Number 5/6(2019)
• Page Start: 539
• Page End: 547
• Publication Date: 2019-11-02
• Subjects: Bacterial translocation mechanisms -- acute pancreatitis -- 16S rDNA; Microbiology -- Periodicals; Microbiology -- Periodicals; Review Literature -- Periodicals; 579
• DOI: 10.1080/1040841X.2019.1621795
• Languages: English
• ISSNs: 1040-841X

Abstract

Abstract: Bacterial translocation is a phenomenon in which live bacteria or their products cross the intestinal barrier to other organs or the circulatory system. Gut translocation of bacteria has been reported in both animal models, and clinical trials often accompany acute pancreatitis and are believed to be linked to patient outcome, especially in severe acute pancreatitis. Therefore, the mechanisms of intestinal bacterial translocation in acute pancreatitis have become a topic of interest in recent years. This review discusses Bacterial translocation in acute pancreatitis, identifies possible mechanisms of action, and provides an overview of the methods used to detect Bacterial translocation in acute pancreatitis. This review also highlights areas that require further research.