Rates of hospitalization associated with the use of aldosterone receptor antagonists in patients with pulmonary arterial hypertension. (August 2019)

• Record Type: Journal Article
• Authors: Corkish, Morgan E.; Devine, Lauren T.; Clarke, Megan M.; Murray, Brian P.; Rose-Jones, Lisa J.
• Is Part Of: Pulmonary circulation. Volume 9:Number 3(2019)
• Publication Date: 2019-08
• Subjects: RV dysfunction -- pulmonary hypertension -- pharmacology; Pulmonary circulation -- Periodicals; Pulmonary circulation; Electronic journals -- Sciences; Periodicals; 616.24005
• DOI: 10.1177/2045894019868422
• Languages: English
• ISSNs: 2045-8932

Abstract

We show that spironolactone use was associated with an increased rate of all-cause hospitalizations, but no difference in hospitalizations for heart failure or pulmonary arterial hypertension, in patients with World Health Organization Group 1 pulmonary arterial hypertension. A possible reason for this finding is confounding from retrospective study design.