Fupyrones A and B, two new α-pyrones from an endophytic fungus, Fusarium sp. F20. Issue 3 (1st February 2020)

• Record Type: Journal Article
• Authors: Gao, Han; Li, Gang; Peng, Xiao-Ping; Lou, Hong-Xiang
• Is Part Of: Natural product research. Volume 34:Issue 3(2020)
• Page Start: 335
• Page End: 340
• Publication Date: 2020-02-01
• Subjects: Endophytes -- natural products -- α-pyrones -- bioactivities; Natural products -- Periodicals; Natural products -- Research -- Periodicals; Biological Factors -- Periodicals; Biological Products -- Periodicals; 547
• DOI: 10.1080/14786419.2018.1531405
• Languages: English
• ISSNs: 1478-6419

Abstract

Abstract: Two new α -pyrones, fupyrones A and B (1 and 2 ) and a biosynthetically related known α -pyrone, 4-methyl-5, 6-dihydro-2 H -pyran-2-one (3 ), were isolated from an endophytic fungus, Fusarium sp. F20, harbored in the stems of the Chinese medicinal plant Mahonia fortunei . Their structures were determined on the basis of spectroscopic data including MS and NMR. The antibacterial efficacies of compounds 1 –3 were evaluated against four selected Gram-positive and Gram-negative bacteria, and their quorum sensing inhibitory activity was also investigated against the test organism, Chromobacterium violaceum . Abstract :