Two new phenolic glycosides from the seeds of Citrullus lanatus. Issue 3 (1st February 2020)

• Record Type: Journal Article
• Authors: Zhang, Xiao-Qian; Shi, Jing; Feng, Shi-Xiu; Xue, Lin; Tian, Li-Ping
• Is Part Of: Natural product research. Volume 34:Issue 3(2020)
• Page Start: 398
• Page End: 404
• Publication Date: 2020-02-01
• Subjects: Citrullus lanatus -- phenolic glycosides -- anti-tumor activity; Natural products -- Periodicals; Natural products -- Research -- Periodicals; Biological Factors -- Periodicals; Biological Products -- Periodicals; 547
• DOI: 10.1080/14786419.2018.1536131
• Languages: English
• ISSNs: 1478-6419

Abstract

Abstract: Two new phenolic glycosides, named lanatusosides C (1 ) and D (2 ), together with four known compounds (3 -6 ), were isolated from the seeds of Citrullus lanatus . Among them, compounds 3 and 4 were isolated from Cucurbitaceae for the first time, and compound 5 was reported from this plant for the first time. Their structures were elucidated by means of extensive spectral analysis, including HR-ESI-MS, 1 H and 13 C NMR techniques. The isolated new compounds were evaluated for cytotoxic activity against HepG2 cell line, of which compound 1 demonstrated weak cytotoxicity against the tested cell line. Abstract :