Cabazitaxel Induced Thrombotic Microangiopathy in a Patient with Prostate Cancer. (19th November 2019)

• Record Type: Journal Article
• Authors: Nlandu, Yannick; Pourcine, Franck; Vong, Ly van phach; Chelly, Jonathan; Jochmans, Sebastien; Mazerand, Sandie; Monchi, Mehran
• Other Names: Korzets Ze'ev Academic Editor.
• Is Part Of: Case reports in nephrology. Volume 2019(2019)
• Publication Date: 2019-11-19
• Subjects: Nephrology -- Periodicals; Kidneys -- Diseases -- Periodicals; Nephrology; Kidneys -- Diseases; Nephrology; Periodicals; Electronic journals; Periodicals; 616.61
• DOI: 10.1155/2019/8591283
• Languages: English
• ISSNs: 2090-6641

Abstract

Abstract : Cancer-associated thrombotic microangiopathy (TMA) refers to a group of disorders characterized by microangiopathic haemolytic anemia, thrombocytopenia, and ischemic organ damage. TMA manifestations can be induced by cancer or by chemotherapy. We report the case of a 64-year-old man with metastatic prostate cancer who experienced a Cabazitaxel-induced TMA manifestation. TMA responds to conservative therapy, dialysis without plasmaphoresis, with progressive recovered renal function.