Cobalt-based metal organic frameworks: a highly active oxidase-mimicking nanozyme for fluorescence "turn-on" assays of biothiol. Issue 4 (16th December 2019)

• Record Type: Journal Article
• Authors: Jin, Tian; Li, Yilei; Jing, Wenjie; Li, Yunchao; Fan, Louzhen; Li, Xiaohong
• Is Part Of: Chemical communications. Volume 56:Issue 4(2020)
• Page Start: 659
• Page End: 662
• Publication Date: 2019-12-16
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/c9cc06840f
• Languages: English
• ISSNs: 1359-7345

Abstract

Abstract : With Co-MOFs as an oxidase-mimicking nanozyme, the AR oxidized product, non-fluorescent resazurin could be reduced to fluorescent resorufin by l -cysteine, which is specifically applied for fluorescence "turn-on" detection of l -cysteine. Abstract : Co-based metal organic frameworks (ZIF-67), working as an oxidase-mimicking nanozyme, can simultaneously catalyze the oxidation of 3, 3′, 5, 5′-tetramethylbenzidine, 2, 2′-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) and Amplex red, exhibiting a high catalytic activity. For Amplex red, two consecutive redox reactions are reported, which is specifically applied for fluorescence "turn-on" detection of biothiols.