Luminescent pro-nitroxide lanthanide complexes for the detection of reactive oxygen species. Issue 3 (11th December 2019)

• Record Type: Journal Article
• Authors: Barré, Richard; Mouchel dit Leguerrier, Damien; Fedele, Lionel; Imbert, Daniel; Molloy, Jennifer K.; Thomas, Fabrice
• Is Part Of: Chemical communications. Volume 56:Issue 3(2020)
• Page Start: 435
• Page End: 438
• Publication Date: 2019-12-11
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/c9cc06524e
• Languages: English
• ISSNs: 1359-7345

Abstract

Abstract : A DOTA-based ligand appended with a pro-nitroxide moiety has been chelated to trivalent Eu and Yb, giving luminescent complexes. Under Fenton conditions both are converted into iminonitroxide and subsequently nitronyl nitroxide complexes. Abstract : The DOTA-based ligand H3 L (5 ) appended with a pro-nitroxide moiety has been synthesized. The europium and ytterbium complexes 5Ln show metal-centred luminescence. They react with ROS in aqueous media to give a transient iminonitroxide and a stable nitronylnitroxide radical authenticated by EPR, with change in luminescence.