Ketene dithioacetals in organic synthesis. Issue 4 (23rd January 2020)

• Record Type: Journal Article
• Authors: Huang, Lifeng; Wu, Jinjing; Hu, Jingang; Bi, Yicheng; Huang, Dayun
• Is Part Of: Tetrahedron letters. Volume 61:Issue 4(2020)
• Publication Date: 2020-01-23
• Subjects: Ketene dithioacetals -- Mechanism -- Nucleophile -- Bond cleavage; Chemistry, Organic -- Periodicals; 547.005
• DOI: 10.1016/j.tetlet.2019.151363
• Languages: English
• ISSNs: 0040-4039

Abstract

Graphical abstract: Highlights: Nucleophilic enethiols. Formation of C-Pd-SR intermediates. CS bond cleavage. Substitution of SR. Reactions of the double bond. Abstract: Ketene dithioacetals were widely used in organic reactions. Herein, recent advances were summarized as five categories according to their triggered mechanisms: (1) nucleophilic enethiols; (2) formation of C-Pd-SR intermediates; (3) CS bond cleavage; (4) substitution of SR; (5) reactions of the double bond. Reactions with alkanes, alkenes, alkynes, aldehydes, isocyanides, indonium ylides et al were discussed. We hope this review will promote future research in this area.