Effect of congenital toxoplasmosis on the encoding of speech in infants. (February 2020)

• Record Type: Journal Article
• Authors: Ferreira, Laís; Valadão, Maria Clara da Silva; Skarzynski, Piotr H.; Sanfins, Milaine Dominici; Biaggio, Eliara Pinto Vieira
• Is Part Of: International journal of pediatric otorhinolaryngology. Volume 129(2020:Feb.)
• Publication Date: 2020-02
• Subjects: Hearing. evoked potentials -- Auditory. child development. infant. toxoplasmosis -- Congenital; Otolaryngology -- Periodicals; Pediatrics -- Periodicals; Otolaryngology -- Periodicals; Pediatrics -- Periodicals; Oto-rhino-laryngologie -- Périodiques; Pédiatrie -- Périodiques; 618.9209751
• DOI: 10.1016/j.ijporl.2019.109767
• Languages: English
• ISSNs: 0165-5876

Abstract

Abstract: Objective: To investigate the effect of congenital toxoplasmosis (CTP) on the Frequency-Following Response (FFR) in infants. Study design: 11 infants diagnosed with CTP and 12 healthy infants with no risk indicators for hearing impairment, aged 29–90 days old. All infants underwent an FFR neurophysiological assessment. The test stimulus was the syllable [da], 40 ms in duration, which was monaurally presented to the right ear at an intensity of 80 dBnHL. Absolute latencies and amplitudes of the V, A, C, D, E, F, and O waves, the slope (μV/ms) and measure between onset (A) and offset (O), were compared between the two groups. Results: Infants with CTP had increased latency of FFR waves V, A, E, F, and O, and decreased amplitude for waves A and F. They also showed a reduction in A–O slope and a higher latency difference between onset (A) and offset (O). Conclusion: The neurophysiological responses of Frequency-Following Response can be influenced by congenital toxoplasmosis. Since, the CTP showed prolongation of the V, A, E, F and O waves and decrease of the amplitude for waves A and F.