Ruthenium-catalyzed meta-C–H bond alkylation of aryl 2-pyridyl ketones. Issue 2 (6th December 2019)

• Record Type: Journal Article
• Authors: Li, Gang; Jia, Chunqi; Cai, Xiaofeng; Zhong, Lei; Zou, Lei; Cui, Xiuling
• Is Part Of: Chemical communications. Volume 56:Issue 2(2020)
• Page Start: 293
• Page End: 296
• Publication Date: 2019-12-06
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/c9cc08624b
• Languages: English
• ISSNs: 1359-7345

Abstract

Abstract : The first example of meta -selective CAr –H bond functionalization of aryl 2-pyridyl ketones has been developed using [Ru( p -cymene)Cl2 ]2 as the catalyst and alkyl bromide as the coupling reagent. Abstract : The first example of meta -selective CAr –H bond functionalization of aryl 2-pyridyl ketones has been developed using [Ru( p -cymene)Cl2 ]2 as the catalyst and alkyl bromide as the coupling reagent. This development provides an efficient strategy for modifying the meta -position of aryl 2-pyridyl ketone skeletons, which are found in various functional molecules.