Electrospinning Piezoelectric Fibers for Biocompatible Devices. Issue 1 (8th November 2019)

• Record Type: Journal Article
• Authors: Azimi, Bahareh; Milazzo, Mario; Lazzeri, Andrea; Berrettini, Stefano; Uddin, Mohammed Jasim; Qin, Zhao; Buehler, Markus J.; Danti, Serena
• Is Part Of: Advanced healthcare materials. Volume 9:Issue 1(2020)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2019-11-08
• Subjects: biomaterials -- biosensors -- lead‐free ceramics -- modeling -- poly(vinylidene fluoride); Biomedical materials -- Periodicals; 610.28
• DOI: 10.1002/adhm.201901287
• Languages: English
• ISSNs: 2192-2640

Abstract

Abstract: The field of nanotechnology has been gaining great success due to its potential in developing new generations of nanoscale materials with unprecedented properties and enhanced biological responses. This is particularly exciting using nanofibers, as their mechanical and topographic characteristics can approach those found in naturally occurring biological materials. Electrospinning is a key technique to manufacture ultrafine fibers and fiber meshes with multifunctional features, such as piezoelectricity, to be available on a smaller length scale, thus comparable to subcellular scale, which makes their use increasingly appealing for biomedical applications. These include biocompatible fiber‐based devices as smart scaffolds, biosensors, energy harvesters, and nanogenerators for the human body. This paper provides a comprehensive review of current studies focused on the fabrication of ultrafine polymeric and ceramic piezoelectric fibers specifically designed for, or with the potential to be translated toward, biomedical applications. It provides an applicative and technical overview of the biocompatible piezoelectric fibers, with actual and potential applications, an understanding of the electrospinning process, and the properties of nanostructured fibrous materials, including the available modeling approaches. Ultimately, this review aims at enabling a future vision on the impact of these nanomaterials as stimuli‐responsive devices in the human body. Abstract : Electrospinning enables the production of smart fibers, including piezoelectrics, with a length scale comparable to the subcellular scale, therefore relevant for biomedical applications. This paper provides a comprehensive review on the fabrication of piezoelectric fibers by encompassing an understanding of the electrospinning process, the obtained piezoelectric properties, the available modeling approaches, and their current and future applications in healthcare.