Charge transport through a water-assisted hydrogen bond in single-molecule glutathione disulfide junctions. Issue 2 (12th December 2019)

• Record Type: Journal Article
• Authors: Yang, Wei-Yu; Zheng, Jueting; Zhang, Xia-Guang; Chen, Li-Chuan; Si, Yu; Huang, Fei-Zhou; Hong, Wenjing
• Is Part Of: Journal of materials chemistry. Volume 8:Issue 2(2019)
• Page Start: 481
• Page End: 486
• Publication Date: 2019-12-12
• Subjects: Materials -- Periodicals; Chemistry, Analytic -- Periodicals; Optical materials -- Research -- Periodicals; Electronics -- Materials -- Research -- Periodicals; 543.0284
• DOI: 10.1039/c9tc05686f
• Languages: English
• ISSNs: 2050-7526

Abstract

Abstract : This work demonstrates that single-molecule conductance measurements can identify reduced and oxidized glutathiones and thus have potential application in clinical diagnosis. Abstract : We report a novel strategy to identify reduced and oxidized glutathiones by employing an STM break junction technique. A mechanism involving a water-assisted hydrogen bond is proposed for the charge transport through the oxidized glutathione junction, and this is verified by both experimental and theoretical findings.