Aggregation-induced emission-active Au nanoclusters for ratiometric sensing and bioimaging of highly reactive oxygen species. Issue 100 (29th November 2019)

• Record Type: Journal Article
• Authors: Ran, Xiang; Wang, Zhenzhen; Pu, Fang; Liu, Zhen; Ren, Jinsong; Qu, Xiaogang
• Is Part Of: Chemical communications. Volume 55:Issue 100(2019)
• Page Start: 15097
• Page End: 15100
• Publication Date: 2019-11-29
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/c9cc08170d
• Languages: English
• ISSNs: 1359-7345

Abstract

Abstract : A nanoprobe based on aggregation-induced emission-active Au nanoclusters for ratiometric sensing and bioimaging of highly reactive oxygen species is constructed. Abstract : We prepared a nanoprobe through self-assembly of gold nanoclusters (AuNCs) and using FITC-modified hyaluronic acid (HA) for ratiometric sensing of highly reactive oxygen species (hROS). Taking advantage of the aggregation-induced emission (AIE) properties of the self-assembled AuNCs, hROS-responsive cleavage of HA, and the ratiometric signal change of dual-emission, the nanoprobe exhibited excellent performance in imaging hROS in living cells.