About the origin of the large Stokes shift in aminoalkyl substituted heptamethine cyanine dyes. Issue 1 (10th December 2019)

• Record Type: Journal Article
• Authors: Sissa, Cristina; Painelli, Anna; Terenziani, Francesca; Trotta, Massimo; Ragni, Roberta
• Is Part Of: Physical chemistry chemical physics. Volume 22:Issue 1(2019)
• Page Start: 129
• Page End: 135
• Publication Date: 2019-12-10
• Subjects: Chemistry, Physical and theoretical -- Periodicals; 541.3
• DOI: 10.1039/c9cp05473a
• Languages: English
• ISSNs: 1463-9076

Abstract

Abstract : Aminoalkyl substituted heptamethine cyanines show a large Stokes shift, ascribed to the geometry relaxation upon photoexcitation that drives the molecule from a distorted ground state structure to a planar and cyanine-like excited state. Abstract : Aminoalkyl-substituted heptamethine cyanine dyes are characterized by a large Stokes shift, an uncommon feature for cyanine molecules yet very promising for their application as fluorescent probes in bioimaging and as light harvesting antennas in biohybrid systems for solar energy conversion. The origin of this photophysical feature has not been adequately explored so far, and a combined experimental and theoretical work is herein provided to shed light on the role played by the central aminoalkyl substituent bound to the heptamethine cyanine backbone in defining the unusual properties of the dye. The spectra recorded in solvents of different polarities point to a marginal role of the medium in the definition of the Stokes shift, which conversely can be ascribed to the relaxation of the molecular geometry upon photoexcitation. This hypothesis is supported by an extensive theoretical investigation of the ground and excited states of the dye. TD-DFT results on the aminoalkyl-substituted dye and its unsubstituted precursor demonstrate a very similar cyanine-like structure for both molecules in the relaxed excited state. Conversely, in the ground state the amino substitution disrupts the conjugation in the polymethine chain, leading to a broken-symmetry, non-planar structure.