A biomimetic cerium-based biosensor for the direct visual detection of phosphate under physiological conditions. Issue 99 (11th November 2019)

• Record Type: Journal Article
• Authors: Rossel, Thibaud; Creus, Marc
• Is Part Of: Chemical communications. Volume 55:Issue 99(2019)
• Page Start: 14894
• Page End: 14897
• Publication Date: 2019-11-11
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/c9cc04840e
• Languages: English
• ISSNs: 1359-7345

Abstract

Abstract : An indicator displacement assay (IDA) was used to probe phosphate ions in an aqueous medium at neutral pH using a dinuclear cerium based complex [Ce2 (HXTA)] 3+ . Abstract : An indicator displacement assay (IDA) was used to probe phosphate ions in an aqueous medium at neutral pH using a dinuclear cerium based complex [Ce2 (HXTA)] 3+ . The homoleptic complex can be used to detect phosphate ions with nanomolar affinity either spectrophotometrically or with the naked-eye. To our knowledge, this is the first dinuclear cerium biomimetic IDA detection system with the highest affinity known to date for selective, naked-eye based phosphate recognition under physiological conditions (pH = 5–7) and even in pure water and complex samples such as sea water.