Neonatal low respiratory tract chlamydia trachomatis infection: Diagnostic and treatment management. (2019)

• Record Type: Journal Article
• Authors: Jouglet, M.; Wuillaume, I.; Buchs, C.; Reix, P.; Schweitzer, C.; Coutier, L.
• Is Part Of: Respiratory medicine case reports. Volume 28(2019)
• Publication Date: 2019
• Subjects: Neonatal low respiratory tract -- Interstitial lung disease -- Chlamydia trachomatis, diagnosis -- Antibiotic therapy -- Infant; chlamydia trachomatis chlamydia t -- Haute autorité de santé HAS -- Sexually transmitted infections STI; Respiratory organs -- Diseases -- Periodicals; Chest -- Diseases -- Periodicals; Respiratory Tract Diseases -- Periodicals; Respiratory System -- Periodicals; Chest -- Diseases; Respiratory organs -- Diseases; Electronic journals; Periodicals; 616.2
• DOI: 10.1016/j.rmcr.2019.100852
• Languages: English
• ISSNs: 2213-0071

Abstract

Abstract: Maternal infection during pregnancy by Chlamydia trachomatis (Chlamydia t. ) can result in neonatal interstitial lung disease. It remains difficult for physicians to establish this diagnosis and to select the best treatment, as there is no recommendation. In these two cases of neonatal low respiratory tract Chlamydia t. infection, we proposed successfully a diagnosis method based on Chlamydia t. determination by PCR, on any type of sampling, but more specifically on urinary and pharyngeal specimens; and a management based on oral antibiotic therapy, Josamycin 50mg/kg/day during 14 days which is commonly well accepted and not invasive.