Fixation free inguinal hernia repair with the 3D dynamic responsive prosthesis ProFlor: Features, procedural steps and long-term results. (2019)

• Record Type: Journal Article
• Authors: Amato, G.; Romano, G.; Goetze, T.; Cicero, L.; Gulotta, E.; Calò, P.G.; Agrusa, A.
• Is Part Of: International journal of surgery open. Volume 21(2019)
• Page Start: 34
• Page End: 43
• Publication Date: 2019
• Subjects: Inguinal hernia -- Dynamic responsive prosthesis -- Biologic response -- Tissue regeneration -- Tissue scaffolds; Surgery -- Periodicals; 617.005
• DOI: 10.1016/j.ijso.2019.10.008
• Languages: English
• ISSNs: 2405-8572

Abstract

Abstract: Background: Static and fixated meshes to repair mobile structures like the groin may seem a procedural incongruence. Inguinal hernia is described as a degenerative disease. Therefore, the objective of disease treatment should be the regeneration of wasted tissue. The fibrotic scar plate, a typical biologic response of conventional static meshes, does not represent tissue regeneration but rather a foreign body reaction. These contrasting aspects seem to be related to high complication rates of inguinal herniorrhaphy. Recent studies concerning the pathophysiology of the groin have led to the development of new concepts for repairing inguinal protrusions. A proprietary designed 3D dynamic responsive implant showing regenerative biologic response is the result of this studies. Materials and methods: A cohort of 389 individuals underwent open inguinal hernia repair with the 3D dynamic responsive implant following a specific surgical technique. Thanks to the inherent dynamic properties, all procedures were performed without need for fixation of the 3D prosthesis. Results: The outcomes of the dynamic hernia repair procedure were reduced postoperative pain and minimized overall complication rates, also long term. Moreover, no patient discomfort or chronic pain was reported. Conclusions: Inguinal hernia repair with the 3D dynamic responsive implant ProFlor seems to represent an effective concept change for the treatment of this widespread degenerative disease. Moving in synchrony with the groin, implanted without need of fixation and acting as a regenerative scaffold, ProFlor™ appears to possess all that is needed for a physiologic and pathogenetical consequent treatment of inguinal protrusions leading to a dramatic lessening of intra- and postoperative complications. Highlights: Repair of inguinal hernias with a 3D dynamic responsive implant. Highlighting steps and results of the procedure. Easy and faster inguinal hernia repair thanks the 3D implant used. Sharp reduction of the adverse events compared to conventional techniques. Regenerative biologic response restores the inguinal barrier wasted by hernia disease.