Synthesis, X-ray structures and antibacterial activities of silver(I) complexes of 1, 3-bis(diphenylphosphano)propane (Dppp) and N, N′-dimethylthiourea (Dmtu). (1st January 2020)

• Record Type: Journal Article
• Authors: Seerat-ur-Rehman, ; Ahmad, Saeed; Choudhary, Muhammad Aziz; Tahir, Muhammad Nawaz; Ali, Imran; Aslam, Muhammad; Fettouhi, Mohammed; Isab, Anvarhusein A.; Alotaibi, Mshari A.; Alharthi, Abdulrahman I.
• Is Part Of: Polyhedron. Volume 175(2020)
• Publication Date: 2020-01-01
• Subjects: Silver(I) complexes -- 1, 3-bis(diphenylphosphano)propane -- Triphenylphosphane -- N, N′-Dimethylthiourea -- Crystal structure -- Antibacterial activity; Chemistry, Inorganic -- Periodicals; Chimie inorganique -- Périodiques; Organometaalverbindingen; Anorganische chemie; 546.05
• DOI: 10.1016/j.poly.2019.114209
• Languages: English
• ISSNs: 0277-5387

Abstract

Graphical abstract: The synthesis, spectroscopic characterization and crystal structures of three silver(I) complexes, [Ag(Dppp)2 ]NO3 ·0.5H2 O (1 ), [Ag2 (Dppp)2 (Dmtu)4 ](NO3 )2 (2 ) and [Ag(PPh3 )2 (Dmtu)2 ]NO3 ·0.5H2 O (3 ) (where Dppp = 1, 3-bis(diphenylphosphano)propane, PPh3 = triphenylphosphane and Dmtu = N, N ′-dimethylthiourea), are presented. In complex 1, two chelating Dppp ligands are coordinated to the Ag(I) ion, each forming a six membered ring. Complex 2 is dinuclear with the individual silver(I) ions bound to two phosphorus atoms of two different Dppp ligands and two sulfur atoms of N, N ′-dimethylthiourea. Complex 3 is mononuclear, having the silver(I) ion coordinated by two PPh3 and two Dmtu ligands. The geometry around the Ag(I) ions in all three complexes is distorted tetrahedral. The complexes were evaluated for antibacterial activity and they were found to exhibit moderate activity against most of the bacteria. Highlights: The crystal structures of [Ag(Dppp)2 ]NO3 ·0.5H2 O (1 ), [Ag2 (Dppp)2 (Dmtu)4 ](NO3 )2 (2 ) and [Ag(PPh3 )2 (Dmtu)2 ]NO3 ·0.5H2 O (3 ). The geometry around the Ag(I) ion in all the complexes is distorted tetrahedral. The antibacterial activity of the complexes, with 2 showing the most significant results. Abstract: Three silver(I) complexes, [Ag(Dppp)2 ]NO3 ·0.5H2 O (1 ), [Ag2 (Dppp)2 (Dmtu)4 ](NO3 )2 (2 ) and [Ag(PPh3 )2 (Dmtu)2 ]NO3 ·0.5H2 O (3 ) (where Dppp = 1, 3-bis(diphenylphosphano)propane, PPh3 = triphenylphosphane and Dmtu = N, N ′-dimethylthiourea), were prepared and characterized by IR and NMR ( 1 H, 13 C and 31 P) spectroscopic methods. The crystal structures of the complexes were determined by X-ray crystallography. All three complexes are ionic, containing nitrate as a counter ion. In complex 1, two Dppp ligands are coordinated to an Ag(I) ion, each acting as a chelating donor to form a six membered ring. Complex 2 is dinuclear with the individual silver(I) ions bound to two phosphorus atoms of two different Dppp ligands and two sulfur atoms of N, N ′-dimethylthiourea. The geometry around the Ag(I) atoms in both complexes is distorted tetrahedral. Complex 3 is mononuclear having the silver(I) ion coordinated by two PPh3 and two Dmtu ligands in a nearly tetrahedral environment. The Dmtu ligands in complexes 2 and 3 are coordinated in a terminal mode. The complexes were evaluated for their antibacterial activity and they were found to exhibit moderate activity against most of the bacteria.