3D Printed Tissues: 3D Printed Cartilage‐Like Tissue Constructs with Spatially Controlled Mechanical Properties (Adv. Funct. Mater. 51/2019). (17th December 2019)

• Record Type: Journal Article
• Authors: de Melo, Bruna A. G.; Jodat, Yasamin A.; Mehrotra, Shreya; Calabrese, Michelle A.; Kamperman, Tom; Mandal, Biman B.; Santana, Maria H. A.; Alsberg, Eben; Leijten, Jeroen; Shin, Su Ryon
• Is Part Of: Advanced functional materials. Volume 29:Number 51(2019)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2019-12-17
• Subjects: bioprinting -- cartilage -- fibrin -- IPN -- spheroids; Materials -- Periodicals; Chemical vapor deposition -- Periodicals; 620.11
• DOI: 10.1002/adfm.201970350
• Languages: English
• ISSNs: 1616-301X

Abstract

Abstract : In article number 1906330, Jeroen Leijten, Su Ryon Shin, and co‐workers develop 3D cartilage‐like tissue through local bioprinting of mesenchymal stem cell spheroids laden with soft and cell stimulating bioink within a mechanically robust hydrogel. This uncoupling of the micro and macro mechanical properties of the 3D printed construct allows it to possess both a chondrogenic microenvironment and the ability to withstand mechanical loads.