Finding Community Modules of Brain Networks Based on PSO with Uniform Design. (17th November 2019)

• Record Type: Journal Article
• Authors: Zhang, Jie; Tang, Lingkai; Liao, Bo; Zhu, Xiaoshu; Wu, Fang-Xiang
• Other Names: Noman Nasimul Academic Editor.
• Is Part Of: BioMed research international. Volume 2019(2019)
• Publication Date: 2019-11-17
• Subjects: Medicine -- Periodicals; Biology -- Periodicals; Biotechnology -- Periodicals; Life sciences -- Periodicals; 610.5
• DOI: 10.1155/2019/4979582
• Languages: English
• ISSNs: 2314-6133

Abstract

Abstract : The brain has the most complex structures and functions in living organisms, and brain networks can provide us an effective way for brain function analysis and brain disease detection. In brain networks, there exist some important neural unit modules, which contain many meaningful biological insights. It is appealing to find the neural unit modules and obtain their affiliations. In this study, we present a novel method by integrating the uniform design into the particle swarm optimization to find community modules of brain networks, abbreviated as UPSO. The difference between UPSO and the existing ones lies in that UPSO is presented first for detecting community modules. Several brain networks generated from functional MRI for studying autism are used to verify the proposed algorithm. Experimental results obtained on these brain networks demonstrate that UPSO can find community modules efficiently and outperforms the other competing methods in terms of modularity and conductance. Additionally, the comparison of UPSO and PSO also shows that the uniform design plays an important role in improving the performance of UPSO.