Peritoneal Dialysis is Feasible as a Bridge to Combined Liver-Kidney Transplant. Issue 1 (January 2018)

• Record Type: Journal Article
• Authors: Jones, Ruth Ellen; Liang, Yun; MacConmara, Malcolm; Hwang, Christine; Saxena, Ramesh
• Is Part Of: Peritoneal dialysis international. Volume 38:Issue 1(2018)
• Page Start: 63
• Page End: 65
• Publication Date: 2018-01
• Subjects: Peritoneal dialysis -- cirrhosis -- ascites -- simultaneous liver-kidney transplantation; Peritoneal dialysis -- Periodicals; Continuous ambulatory peritoneal dialysis -- Periodicals; 617.461059
• DOI: 10.3747/pdi.2017.00124
• Languages: English
• ISSNs: 0896-8608

Abstract

Patients with combined liver and kidney failure may remain on dialysis for years while awaiting simultaneous liver-kidney transplantation (SLKT). The role of peritoneal dialysis (PD) in patients with advanced liver and kidney failure awaiting SLKT remains to be defined. We present our single-institution experience with PD in cirrhotics, 3 of whom went on to receive successful SLKT. Patients initiated in our PD program between 2006 and 2016 who had both liver and kidney failure were identified. Medical and dialysis records were reviewed retrospectively. Outcomes included mortality, transplantation status, hospitalizations, need for large-volume paracentesis (LVP), peritonitis rates, PD treatment longevity, and albumin level. Twelve patients with combined liver and kidney failure were treated in our PD program. No patients died and 3 patients received SLKT. Four patients remain listed for transplantation. There was no need for LVP after initiating dialysis. The rate of peritonitis was 0.2 events per patient per year, most commonly due to coagulase-negative Staphylococcus . Our data illustrate that PD is a viable bridging therapy for patients with liver and kidney failure who await SLKT.