One‐pot synthesis of benzimidazole‐pyrazines and their anticancer activities. (7th November 2019)
- Record Type:
- Journal Article
- Title:
- One‐pot synthesis of benzimidazole‐pyrazines and their anticancer activities. (7th November 2019)
- Main Title:
- One‐pot synthesis of benzimidazole‐pyrazines and their anticancer activities
- Authors:
- Li, Yingfen
Wei, Xian
Bai, Song
Xu, Zhi‐Gang
Lv, Menglan - Abstract:
- Abstract: The skeleton of fused benzimidazole‐pyrazine was constructed via an Ugi/deprotection/cyclization (UDC) and hydroamination cascade reaction. This four‐step reaction was carried out in a one‐pot procedure with only one‐time column chromatography purification. The representative compound 7b exhibited 67% cell growth inhibitory activity against human breast cancer cell line MDA‐MB‐453 at the concentration of 10μM. Abstract :
- Is Part Of:
- Journal of heterocyclic chemistry. Volume 56:Number 12(2019)
- Journal:
- Journal of heterocyclic chemistry
- Issue:
- Volume 56:Number 12(2019)
- Issue Display:
- Volume 56, Issue 12 (2019)
- Year:
- 2019
- Volume:
- 56
- Issue:
- 12
- Issue Sort Value:
- 2019-0056-0012-0000
- Page Start:
- 3429
- Page End:
- 3434
- Publication Date:
- 2019-11-07
- Subjects:
- Heterocyclic compounds -- Periodicals
547.59 - Journal URLs:
- http://onlinelibrary.wiley.com/ ↗
- DOI:
- 10.1002/jhet.3701 ↗
- Languages:
- English
- ISSNs:
- 0022-152X
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 4998.200000
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 12470.xml