Synthesis of substituted quinolines via B(C6F5)3‐catalyzed aniline‐aldehyde‐pyruvate oxidative annulation. (30th October 2019)
- Record Type:
- Journal Article
- Title:
- Synthesis of substituted quinolines via B(C6F5)3‐catalyzed aniline‐aldehyde‐pyruvate oxidative annulation. (30th October 2019)
- Main Title:
- Synthesis of substituted quinolines via B(C6F5)3‐catalyzed aniline‐aldehyde‐pyruvate oxidative annulation
- Authors:
- Ling, Fei
Chen, Jiachen
Xie, Zhen
Hou, Huacui
Pan, Zhentao
Feng, Cong
Shen, Haiwei
Zhong, Weihui - Abstract:
- Abstract: A metal‐free method to construct quinoline derivatives via B(C6 F5 )3 ‐catalyzed cyclization of anilines with aldehyde derivatives and pyruvates is described. This three‐component cascade reaction provides an efficient approach for the easy access to various substituted quinoline‐4‐carboxylic esters with 71% to 92% yield. The utility of this methodology was further demonstrated by gram‐scale formal synthesis of the antimalarial drug DDD107498. Abstract :
- Is Part Of:
- Journal of heterocyclic chemistry. Volume 56:Number 12(2019)
- Journal:
- Journal of heterocyclic chemistry
- Issue:
- Volume 56:Number 12(2019)
- Issue Display:
- Volume 56, Issue 12 (2019)
- Year:
- 2019
- Volume:
- 56
- Issue:
- 12
- Issue Sort Value:
- 2019-0056-0012-0000
- Page Start:
- 3333
- Page End:
- 3342
- Publication Date:
- 2019-10-30
- Subjects:
- Heterocyclic compounds -- Periodicals
547.59 - Journal URLs:
- http://onlinelibrary.wiley.com/ ↗
- DOI:
- 10.1002/jhet.3730 ↗
- Languages:
- English
- ISSNs:
- 0022-152X
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 4998.200000
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 12470.xml