(+)- and (−)-actinoxocine, and actinaphthorans A–B, C-ring expansion and cleavage angucyclinones from a marine-derived Streptomyces sp. Issue 24 (31st October 2019)

• Record Type: Journal Article
• Authors: Zhang, Shumin; Zhang, Lu; Fu, Xinzhen; Li, Zhi; Guo, Lin; Kou, Lijuan; Liu, Ming; Xie, Zeping
• Is Part Of: Organic chemistry frontiers. Volume 6:Issue 24(2019)
• Page Start: 3925
• Page End: 3928
• Publication Date: 2019-10-31
• Subjects: Chemistry, Organic -- Periodicals; 547.005
• DOI: 10.1039/c9qo01154d
• Languages: English
• ISSNs: 2052-4110

Abstract

Abstract : A pair of enantiomeric C-ring expansion angucyclinones with an unprecedented epoxybenzo[ f ]naphtho[1, 8- bc ]oxocine carbon skeleton, and two unique C-ring cleavage analogues, were isolated from a marine-derived Streptomyces sp. Abstract : (+)- and (−)-actinoxocine (1 ), a pair of enantiomeric C-ring expansion angucyclinones, featuring a unique epoxybenzo[ f ]naphtho[1, 8- bc ]oxocine carbon skeleton, and two unusual C-ring cleavage analogues, actinaphthorans A–B (2–3 ), were isolated from a marine-derived Streptomyces sp. Their structures and absolute configurations were assigned by spectroscopic analysis, X-ray diffraction and CD calculations.