Malnutrition diagnosed by controlling nutrition status is a negative predictor of life prognosis in aortic arch aneurysm patients treated with thoracic endovascular aneurysm repair. (February 2020)

• Record Type: Journal Article
• Authors: Inoue, Kentaro; Matsumoto, Takuya; Yamashita, Sho; Yoshiga, Ryosuke; Yoshiya, Keiji; Matsubara, Yutaka; Matsuda, Daisuke; Morisaki, Koichi; Furuyama, Tadashi; Mori, Masaki
• Is Part Of: Vascular. Volume 28:Number 1(2020)
• Page Start: 31
• Page End: 41
• Publication Date: 2020-02
• Subjects: Controlling Nutrition Status -- aortic arch aneurysm -- malnutrition -- thoracic endovascular aneurysm repair; 616.13
• DOI: 10.1177/1708538119869458
• Languages: English
• ISSNs: 1708-5381

Abstract

Objectives: Controlling Nutritional Status (CONUT) is a useful screening tool for malnutrition in patients with various diseases; however, how CONUT-diagnosed malnutrition affects patients with aortic arch aneurysm is unknown. This study aimed to reveal the utility of CONUT for detecting the patients with high-risk aortic arch aneurysm with malnutrition. Methods: Sixty patients treated for aortic arch aneurysms with elective thoracic endovascular aneurysm repair from 2009 to 2015 were retrospectively analyzed at a single institution. Preoperative nutrition status was evaluated by CONUT, and a CONUT score ≥ 3 was defined as malnutrition. The influence of malnutrition on the patients' overall survival, aneurysm-related death-free rates, and prevalence of re-interventions were also analyzed. Results: Twenty-three patients were diagnosed with malnutrition. Overall survival was significantly lower in the malnutrition group ( P = 0.0036). The multivariate Cox proportional hazard analysis revealed that age ( P < 0.0001) and malnutrition ( P = 0.0457) were negative predictors of overall survival. Conversely, the two groups did not differ significantly in aneurysm-related death-free rates ( P = 0.7879) and the prevalence of re-interventions ( P = 0.7879). Conclusions: Malnutrition diagnosed by CONUT as well as age is a negative predictor of survival prognosis in patients with aortic arch aneurysm.