Excited-state locked amino analogues of the green fluorescent protein chromophore with a giant Stokes shift. Issue 66 (26th November 2019)

• Record Type: Journal Article
• Authors: Zaitseva, Snizhana O.; Farkhutdinova, Dilara A.; Baleeva, Nadezhda S.; Smirnov, Alexander Yu.; Zagudaylova, Marina B.; Shakhov, Aleksander M.; Astafiev, Artyom A.; Baranov, Mikhail S.; Bochenkova, Anastasia V.
• Is Part Of: RSC advances. Volume 9:Issue 66(2019)
• Page Start: 38730
• Page End: 38734
• Publication Date: 2019-11-26
• Subjects: Chemistry -- Periodicals; 540.5
• DOI: 10.1039/c9ra08808c
• Languages: English
• ISSNs: 2046-2069

Abstract

Abstract : We design a new class of excited-state locked GFP chromophores which intrinsically exhibit a very large Stokes shift. Abstract : We design a novel class of excited-state locked GFP chromophores by introducing an amine group at the double exo -bond and a difluoroboryl bridge. We show that these chromophores intrinsically exhibit a very large Stokes shift of 1 eV. Further tuning through chemical modifications of their aryl substituents makes them environmentally sensitive.