Neurodevelopmental Outcomes of Very Low Birth Weight Infants at 18–24 Months, Corrected Gestational Age in a Tertiary Health Centre: A Prospective Cohort Study. (21st February 2019)

• Record Type: Journal Article
• Authors: Oommen, Samuel P; Santhanam, Sridhar; John, Hima; Roshan, Reeba; Swathi, T O; Padankatti, Caroline; Grace, Hannah; Beulah, Rachel; Jana, Atanu Kumar; Kumar, Manish; Thomas, Niranjan; Yadav, Bijesh
• Is Part Of: Journal of tropical pediatrics. Volume 65:Number 6(2019:Dec.)
• Page Start: 552
• Page End: 560
• Publication Date: 2019-02-21
• Subjects: Pediatrics -- Periodicals; Tropical medicine -- Periodicals; Pediatrics -- Periodicals; Tropical Medicine -- Periodicals; Environmental Health -- Periodicals; Infant; Child; 618.929883
• DOI: 10.1093/tropej/fmz006
• Languages: English
• ISSNs: 0142-6338

Abstract

Abstract: Objective: To determine the prevalence and risk factors for poor neurodevelopmental outcome in a cohort of very low birth weight (VLBW) infants. Subjects and methods: Four hundred and twenty-two infants of a total of 643 VLBW survivors from a teaching hospital in South India were followed up to assess their neurodevelopmental outcomes. Results: Among the 422 children who completed the assessment, results of 359 children whose assessments were done between 18 and 24 months were analysed. Thirty-seven children (10.31%) had poor neurodevelopmental outcome, six children [1.67%] had cerebral palsy, one child had visual impairment and another had hearing impairment. Poor post-natal growth was independently associated with poor neurodevelopmental outcomes in the multivariate analysis ( p = 0.045). Neonatal complications were not associated with the developmental outcome. Conclusion: Despite lower rates of neonatal complications compared with Western cohorts, significant proportion of VLBW infants had poor neurodevelopmental outcomes. Poor post-natal growth was an important determinant of the developmental outcome