Invasive Lobular Carcinoma With Extensive Clear Cells: A Pitfall in Diagnosis. (April 2020)

• Record Type: Journal Article
• Authors: Kavesh, Mark H.; Sanchez, Daniel; Asirvatham, Jaya Ruth
• Is Part Of: International journal of surgical pathology. Volume 28:Number 2(2020)
• Page Start: 169
• Page End: 172
• Publication Date: 2020-04
• Subjects: breast -- carcinoma -- lobular carcinoma -- breast clear cell tumors -- clear cell; Pathology, Surgical -- Periodicals; 617.07
• DOI: 10.1177/1066896919881705
• Languages: English
• ISSNs: 1066-8969

Abstract

Carcinomas in the breast with a predominantly clear cytoplasm are rare. In this article, we review the differential diagnosis of clear cell breast neoplasms and report a case of invasive lobular carcinoma with extensive clear cell morphology that was diagnosed as invasive ductal carcinoma, not otherwise specified, on ultrasound-guided biopsy. Lobular carcinomas with extensive clear cell change are unusual, but must be considered when evaluating a clear cell neoplasm in the breast.