A Reconfigurable DNA Accordion Rack. Issue 11 (14th February 2018)

• Record Type: Journal Article
• Authors: Choi, Yeongjae; Choi, Hansol; Lee, Amos C.; Lee, Hyunung; Kwon, Sunghoon
• Is Part Of: Angewandte Chemie international edition. Volume 57:Issue 11(2018)
• Page Start: 2811
• Page End: 2815
• Publication Date: 2018-02-14
• Subjects: DNA nanomachines -- DNA nanotechnology -- DNA structures -- nanopores -- self-assembly; Chemistry -- Periodicals; 540
• DOI: 10.1002/anie.201709362
• Languages: English
• ISSNs: 1433-7851

Abstract

Abstract: DNA nanostructure‐based mechanical systems that control the distance between elements of interest have demonstrated great potential for various applications, including nanoplasmonic systems, molecular reactors, and other nanotechnology platforms. However, previously reported systems could not collectively manipulate a 2D or 3D nanoscale network of elements to various forms in multiple stages. A reconfigurable DNA accordion rack structure is introduced that is a DNA beam lattice that changes its conformation with a small amount of short‐length DNA locks as the controlling input. The lattice shape of the 2D DNA accordion rack and the diameter and the height of the 3D DNA nanotubular structure made of the DNA accordion rack could be controlled. Furthermore, by sequentially repeating the detachment and the attachment of the different DNA locks using strand displacement, the shape reconfiguration was repeatedly carried out. Abstract : A reconfigurable DNA accordion rack structure, namely a DNA beam lattice with flexible joints between the adjacent beams, changes its conformation with a small amount of short‐length DNA locks as the controlling input. The lattice shape of the 2D DNA accordion rack and the diameter and the height of the 3D DNA nanotube made of the DNA accordion rack could be controlled.