Cell‐Membrane Engineering: Engineering Cell Surface Function with DNA Origami (Adv. Mater. 46/2017). Issue 46 (7th December 2017)

• Record Type: Journal Article
• Authors: Akbari, Ehsan; Mollica, Molly Y.; Lucas, Christopher R.; Bushman, Sarah M.; Patton, Randy A.; Shahhosseini, Melika; Song, Jonathan W.; Castro, Carlos E.
• Is Part Of: Advanced materials. Volume 29:Issue 46(2017)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2017-12-07
• Subjects: cell surface engineering -- DNA nanotechnology -- DNA origami -- intercellular adhesion -- membrane functionalization; Materials -- Periodicals; Chemical vapor deposition -- Periodicals; 620.11
• DOI: 10.1002/adma.201770328
• Languages: English
• ISSNs: 0935-9648

Abstract

Abstract : DNA‐origami nanodevices are embedded on the membrane of two cells by Jonathan W. Song, Carlos E. Castro, and co‐workers in article number 1703632 . The devices are anchored to the cell via a DNA base‐pairing attachment to a cholesterol‐labeled DNA strand embedded in the membrane. The two pairs of nanostructures (shown here on the right) mediate adhesion between the cells via a sequence‐specific DNA binding interaction.