Smart combination of β-cyclodextrin polymer-conjugated magnetic nanosorbent for potential adsorption of deoxyribonucleic acid. Issue 6 (13th April 2019)

• Record Type: Journal Article
• Authors: Ying Hwa, Goh; Yih Hui, Boon; Jairaj Moses, Emmanuel; Shahriman, Mohamad Shariff; Md Yusoff, Masrudin; Yahaya, Noorfatimah; Sambasevam, Kavirajaa Pandian; Surikumaran, Hemavathy; Chandrasekaram, Kumuthini; Raoov, Muggundha
• Is Part Of: Separation science and technology. Volume 54:Issue 6(2019)
• Page Start: 902
• Page End: 915
• Publication Date: 2019-04-13
• Subjects: β-Cyclodextrin -- adsorption -- magnetic nanoparticles -- biomedical application -- inclusion complex; Separation (Technology) -- Periodicals; 660.284205
• DOI: 10.1080/01496395.2018.1524485
• Languages: English
• ISSNs: 0149-6395

Abstract

ABSTRACT: We reported the synthesis and characterization of Fe3 O4 magnetic nanoparticles modified β-cyclodextrin polymer (MNP@βCD-TDI) for the adsorption of deoxyribonucleic acid (DNA). The synthesized MNP@βCD-TDI was characterized by Fourier Transform Infra-Red spectroscopy and Vibrating Sample Magnetometer. Experiments were performed in a batch mode and parameters that affected the DNA adsorption were investigated. An evaluation of the adsorption behavior revealed that Freundlich model and pseudo-second-order fit the equilibrium data. The adsorption efficiency of DNA was found to be at 70 ± 5 % after being recycled three times. This study could be used as a general platform for future work on DNA adsorption and enrichment.