Efficient route to RIKEN click probes for glycoconjugation. Issue 2 (12th February 2019)

• Record Type: Journal Article
• Authors: Nakamura, Kayo; Tsubokura, Kazuki; Kurbangalieva, Almira; Nakao, Yoichi; Murase, Takefumi; Shimoda, Taiji; Tanaka, Katsunori
• Is Part Of: Journal of carbohydrate chemistry. Volume 38:Issue 2(2019)
• Page Start: 127
• Page End: 138
• Publication Date: 2019-02-12
• Subjects: Albumin -- drug delivery system -- glycocluster -- glycoconjugation -- RIKEN click probe; Carbohydrates -- Periodicals; 547.78
• DOI: 10.1080/07328303.2019.1578886
• Languages: English
• ISSNs: 0732-8303

Abstract

Abstract: A convenient route to RIKEN click probes for glycoconjugation to the amino groups of lysines was established. N -Glycoclusters prepared with human serum albumin by the new method showed the same cell interaction profiles as those synthesized previously. The new route has thus significantly expanding the applicability to glycoconjugation and drug delivery systems. Graphical Abstract: