Feline alimentary lymphoma: a guide to cytological and histopathological diagnosis for the general practitioner. (2nd October 2019)

• Record Type: Journal Article
• Authors: Irving, Jennifer; Dobromylskyj, Melanie J; Holmes, Emma
• Is Part Of: Companion animal. Volume 24:Number 9(2019)
• Page Start: 466
• Page End: 471
• Publication Date: 2019-10-02
• Subjects: cytology -- feline -- gastrointestinal tract -- histopathology -- lymphoma -- pathology; Veterinary medicine -- Periodicals; Pet medicine -- Periodicals; 636.08905
• DOI: 10.12968/coan.2019.0033
• Languages: English
• ISSNs: 2053-0889

Abstract

Abstract : Lymphoma is the most common neoplasm in domestic cats and alimentary lymphoma is now the most common anatomical site. This article aims to highlight and explain the shift from FeLV-positive multicentric to FeLV-negative alimentary lymphomas, and to explain the cytological and histopathological methods of diagnosing and classifying alimentary lymphoma, in a way that is useful to the general practitioner. Alimentary lymphoma (AL) in felines can be histologically graded into low-, intermediate- and high-grade lymphoma. Low-grade AL has a fair prognosis, while intermediate- and high-grade have poorer prognoses. Transmural invasion by neoplastic lymphocytes also carries a poor prognosis. Large granular lymphocyte lymphoma is a histological sub-classification determined by cell morphology, can be of any grade, and the prognosis is very poor.