Plasma Cell Granuloma of the Thyroid: A Conservative Approach to a Rare Condition and Review of the Literature. (26th January 2010)

• Record Type: Journal Article
• Authors: Barber, W. A.; Fernando, M.; Chadwick, D. R.
• Other Names: Beck-Peccoz Paolo Academic Editor.
• Is Part Of: Journal of thyroid research. Volume 2010(2010)
• Publication Date: 2010-01-26
• Subjects: Thyroid gland -- Cancer -- Periodicals; Thyroid gland -- Diseases -- Periodicals; 616.99444
• DOI: 10.4061/2010/840469
• Languages: English
• ISSNs: 2090-8067

Abstract

Abstract : Introduction . We present a case of an 89-year-old female who attended our surgical endocrine clinic with a 3-month history of a left-sided neck lump. There was no past medical history of thyroid disease. Methods . Following examination and further investigation, including core biopsy, a diagnosis of plasma cell granuloma of the thyroid was made. Biochemical testing of thyroid function and Thyroid Peroxidase Antibody was in-keeping with an associated Hashimoto's thyroiditis. Results . The patient was treated conservatively with thyroxine and regularly seen in clinic. TSH levels improved and the lump showed signs of regression. Conclusion . Plasma cell granuloma of the thyroid is rare with only 16 previously reported cases. We present a new approach to management without the use of surgery or steroids. The literature is reviewed comparing clinico-pathological features and management of other reported cases.