The Survival Strategies of Malaria Parasite in the Red Blood Cell and Host Cell Polymorphisms. (25th July 2010)

• Record Type: Journal Article
• Authors: Dhangadamajhi, Gunanidhi; Kar, Shantanu Kumar; Ranjit, Manoranjan
• Other Names: Wahlgren Mats Academic Editor.
• Is Part Of: Malaria research and treatment. Volume 2010(2010)
• Publication Date: 2010-07-25
• Subjects: Malaria -- Periodicals; Malaria -- Research -- Periodicals; Malaria -- Treatment -- Periodicals; Malaria -- Prevention -- Periodicals; 616.9362005
• DOI: 10.4061/2010/973094
• Languages: English
• ISSNs: 2090-8075

Abstract

Abstract : Parasite growth within the erythrocyte causes dramatic alterations of host cell which on one hand facilitates nutrients acquisition from extracellular environment and on other hand contributes to the symptoms of severe malaria. The current paper focuses on interactions between the Plasmodium parasite and its metabolically highly reduced host cell, the natural selection of numerous polymorphisms in the genes encoding hemoglobin and other erythrocyte proteins.