Beware of False-Positive FDG PET/CT Interpretations for Presacral Recurrent Rectal Cancer. (May 2019)

• Record Type: Journal Article
• Authors: Pennings, Jan P.; de Haas, Robbert J.; de Jong, Koert P.; Dierckx, Rudi A.J.O.; Kwee, Thomas C.
• Is Part Of: Clinical nuclear medicine. Volume 44:Number 5(2019)
• Publication Date: 2019-05
• Subjects: diffusion-weighted MRI -- FDG PET/CT -- MRI -- presacral -- rectal cancer -- recurrent; Nuclear medicine -- Periodicals; Radioisotope scanning -- Periodicals; Nuclear Medicine -- Periodicals; 616.07575
• DOI: 10.1097/RLU.0000000000002545
• Languages: English
• ISSNs: 0363-9762

Abstract

Abstract : Abstract: FDG PET/CT is considered an accurate method for the detection of recurrent rectal cancer in the pelvis. Excess presacral soft tissue is found in up to half of patients after (chemo)radiation and surgery for rectal cancer, and usually represents fibrosis that is metabolically inactive. However, presacral soft tissue that is FDG avid is generally considered suspicious for recurrent cancer. Nevertheless, FDG avidity in the presacral space not uncommonly proves to be due to benign inflammatory changes, and additional MRI may be diagnostically useful, as demonstrated in the presented 2 cases.