Direction of the Biopsy Needle in Ultrasound-Guided Renal Biopsy Impacts Specimen Adequacy and Risk of Bleeding. Issue 4 (November 2019)

• Record Type: Journal Article
• Authors: Sawicka, Katherine; Hassan, Noman; Dumaine, Chance; Budd, Allison; Wall, Chris; Banerjee, Tamalina; Lim, Hyun J.; Mondal, Prosanta; Barton, James; Moser, Michael A.J.
• Is Part Of: Canadian Association of Radiologists journal. Volume 70:Issue 4(2019)
• Page Start: 361
• Page End: 366
• Publication Date: 2019-11
• Subjects: Hemorrhage -- Kidney cortex -- Kidney medulla -- Needle biopsy -- Ultrasound; Radiology, Medical -- Periodicals; Radiology, Medical -- Canada -- Periodicals; 616.0757
• DOI: 10.1016/j.carj.2018.11.006
• Languages: English
• ISSNs: 0846-5371

Abstract

Introduction: Although medical factors such as hypertension and coagulopathy have been identified that are associated with hemorrhage after renal biopsy, little is known about the role of technical factors. The purpose of our study was to examine the effects of biopsy needle direction on renal biopsy specimen adequacy and bleeding complications. Methods: Two hundred and forty-two patients who had undergone ultrasound-guided renal biopsies were included. A printout of the ultrasound picture taken at the time of the biopsy was used to measure the biopsy angle ("angle of attack" [AOA]) and to determine if the biopsy needle was aimed at the upper or lower pole and if the medulla was targeted or avoided. Results: Of the 3 groups of biopsy angle, an AOA of between 50°–70° yielded the most glomeruli per core ( P = .001) and the fewest inadequate specimens (4% vs 15% for > 70°, and 9% for < 50°, P = .038). Biopsy directed at a pole vs an interpolar region resulted in fewer inadequate specimens (8% vs 23%, P = .005), while biopsies that were medulla-avoiding resulted in fewer inadequate specimens (5% vs 16%, P = .004) and markedly reduced bleeding complications (12% vs 46%, P < .001) compared to biopsies where the medulla was entered. Discussion: An AOA of approximately 60°, aiming at the poles, and avoiding the medulla were each associated with fewer inadequate biopsies and bleeding complications. While biopsy of the medulla is necessary for some diagnoses, the increased bleeding risk emphasizes the need for communication between nephrologist, pathologist, and radiologist.