Two new triterpenes from the roots of Pfaffia glomerata. Issue 5 (4th May 2019)

• Record Type: Journal Article
• Authors: Lian, Lian; Feng, Yuan; Li, Yan-Wu; Bei, Bei; Tang, Ye-Tian; Wang, Hao; Feng, Qing-Mei; Chen, Gang
• Is Part Of: Journal of Asian natural products research. Volume 21:Issue 5(2019)
• Page Start: 442
• Page End: 448
• Publication Date: 2019-05-04
• Subjects: Amaranthaceae -- Pfaffia paniculata -- triterpenoids -- anti-inflammation; Materia medica -- Asia -- Periodicals; Pharmacognosy -- Asia -- Periodicals; Medicinal plants -- Asia -- Periodicals; Medicine, Oriental -- Asia -- Periodicals; 615.321095
• DOI: 10.1080/10286020.2018.1446949
• Languages: English
• ISSNs: 1028-6020

Abstract

Abstract: Pfaffia paniculata is a commercialized dietary supplement used as the substitute for the Asian ginseng in Brazil. We conducted the systematic isolation of the EtOAc fraction with anti-inflammatory effect and two new triterpenoids, along with 26 known compounds were characterized by means of MS and NMR analysis. Interestingly, the new compound 1 is the first seco-ring triterpenoid reported in the Pfaffia genus. Furthermore, among the known compounds, 14 and 15 exhibited anti-inflammatory activity in Caco-2 cells, but two new compounds showed no anti-inflammatory. Abstract :