MOS6 and TN13 in plant immunity. (3rd April 2018)

• Record Type: Journal Article
• Authors: Lüdke, Daniel; Roth, Charlotte; Hartken, Denise; Wiermer, Marcel
• Is Part Of: Plant signaling & behavior. Volume 13:Number 4(2018)
• Publication Date: 2018-04-03
• Subjects: TIR-NBS13 -- IMPORTIN-α3 -- MOS6 -- plant immunity -- Arabidopsis; Plant ecophysiology -- Periodicals; Plant cellular signal transduction -- Periodicals; Plant cellular signal transduction; Plant ecophysiology; Periodicals; Electronic journals; 581
• DOI: 10.1080/15592324.2018.1454816
• Languages: English
• ISSNs: 1559-2316

Abstract

ABSTRACT: The Arabidopsis nuclear transport receptor IMPORTIN-α3/MOS6 (MODIFIER OF SNC1, 6 ) is required for constitutive defense responses of the auto-immune mutant snc1 (suppressor of npr1-1, constitutive 1 ) and contributes to basal disease resistance, suggesting a role in nuclear import of defense-regulatory cargo proteins. We recently showed that MOS6 selectively interacts with TN13, a TIR-NBS protein involved in basal resistance to Pseudomonas syringae pv. tomato (Pst ) DC3000 lacking the effectors AvrPto and AvrPtoB. Consistent with a predicted N-terminal transmembrane domain, TN13 localizes to the endoplasmic reticulum (ER) and the nuclear envelope (NE) where it interacts with MOS6 in a transient expression assay. Here, we propose a model that summarizes the subcellular localization, association and function of TN13 and MOS6 in plant defense signaling.