The Racoon Eye Sign in the Investigation of Dementia Using 18F-Florbetaben. (May 2019)

• Record Type: Journal Article
• Authors: Ordidge, Katherine; Gandy, Nemi; Arshad, Mubarik; Win, Zarni
• Is Part Of: Clinical nuclear medicine. Volume 44:Number 5(2019)
• Publication Date: 2019-05
• Subjects: Alzheimer disease -- β-amyloid -- 18F-florbetaben; Nuclear medicine -- Periodicals; Radioisotope scanning -- Periodicals; Nuclear Medicine -- Periodicals; 616.07575
• DOI: 10.1097/RLU.0000000000002502
• Languages: English
• ISSNs: 0363-9762

Abstract

Abstract : Abstract: Differentiating Alzheimer disease (AD) from other forms of cognitive impairment and from normal aging can be challenging. As a consequence, the diagnosis of AD can be delayed, often occurring too late for meaningful intervention. The role of β-amyloid plaques in the pathogenesis of AD provides a target for highly sensitive and specific image quantification of amyloid plaque burden using β-amyloid PET ( 18 F-florbetaben). Here we present the case of a 77-year-old woman with increasing memory impairment and striking white matter changes on MRI, with the "racoon eye" sign on 18 F-florebetaben PET imaging.