Prostate Cancer Pulmonary Metastasis Presenting as a Ground-Glass Pulmonary Nodule on 68Ga-PSMA-11 PET/CT. (May 2019)

• Record Type: Journal Article
• Authors: Lubin, David J.; Holden, Stuart B.; Rettig, Matthew B.; Reiter, Robert E.; King, Christopher R.; Lee, Jay M.; Wallace, Dean W.; Calais, Jeremie
• Is Part Of: Clinical nuclear medicine. Volume 44:Number 5(2019)
• Publication Date: 2019-05
• Subjects: ground-glass pulmonary nodule -- metastasis -- prostate cancer -- PSMA PET/CT; Nuclear medicine -- Periodicals; Radioisotope scanning -- Periodicals; Nuclear Medicine -- Periodicals; 616.07575
• DOI: 10.1097/RLU.0000000000002499
• Languages: English
• ISSNs: 0363-9762

Abstract

Abstract : Abstract: 68 Ga–prostate-specific membrane antigen 11 (PSMA) PET/CT imaging accurately depicts metastatic prostate adenocarcinoma (PCa). Pulmonary metastases of PCa are often overlooked on follow-up imaging in patients after initial treatment and following androgen deprivation therapy. Here we present a rare case of biopsy-proven PCa pulmonary metastasis with a ground-glass appearance. The increased PSMA expression and the evolving CT features of the solid component of the ground-glass nodule detected by PSMA PET/CT imaging led to surgical resection and PET/CT-guided therapy.