Metal‐Catalyzed Remote Functionalization of ω‐Ene Unsaturated Ethers: Towards Functionalized Vinyl Species. Issue 27 (1st June 2018)

• Record Type: Journal Article
• Authors: Ho, Guo‐Ming; Judkele, Lina; Bruffaerts, Jeffrey; Marek, Ilan
• Is Part Of: Angewandte Chemie international edition. Volume 57:Issue 27(2018)
• Page Start: 8012
• Page End: 8016
• Publication Date: 2018-06-01
• Subjects: cross-coupling -- isomerization -- nickel -- remote functionalization -- zirconium; Chemistry -- Periodicals; 540
• DOI: 10.1002/anie.201802434
• Languages: English
• ISSNs: 1433-7851

Abstract

Abstract: The combined ruthenium‐catalyzed chain walking with the nickel‐catalyzed cross‐coupling reaction of ω‐alkenyl ethers provide a unique entry to functionalized vinyl species. This transformation illustrates the power and flexibility of remote functionalization by demonstrating the compatibility of two independent reactions involving unrelated sites. Abstract : Walking a tightrope : The combined ruthenium‐catalyzed chain walking with the nickel‐catalyzed cross‐coupling reaction of ω‐alkenyl ethers provide a unique entry to functionalized vinyl species. This transformation illustrates the power and flexibility of remote functionalization by demonstrating the compatibility of two independent reactions involving unrelated sites.