A Radical Revolution for Trifluoromethoxylation. Issue 27 (11th June 2018)

• Record Type: Journal Article
• Authors: Sahoo, Basudev; Hopkinson, Matthew N.
• Is Part Of: Angewandte Chemie international edition. Volume 57:Issue 27(2018)
• Page Start: 7942
• Page End: 7944
• Publication Date: 2018-06-11
• Subjects: fluorine -- methodology development -- photochemistry -- radical chemistry -- trifluoromethoxylation; Chemistry -- Periodicals; 540
• DOI: 10.1002/anie.201804939
• Languages: English
• ISSNs: 1433-7851

Abstract

Abstract : The study of OCF3 ‐substituted molecules is somewhat hampered by a lack of diverse synthetic methods to access them. By introducing a new mild and practical reaction system for accessing the . OCF3 radical, a recent study by Liu, Ngai, and co‐workers has the potential to dramatically expand the scope of direct trifluoromethoxylation. The features of this ground‐breaking system are discussed and placed into context with other recent advances on nucleophilic trifluoromethoxylation.