Synthesis of N−H Bearing Imidazolidinones and Dihydroimidazolones Using Aza‐Heck Cyclizations. (19th August 2018)
- Record Type:
- Journal Article
- Title:
- Synthesis of N−H Bearing Imidazolidinones and Dihydroimidazolones Using Aza‐Heck Cyclizations. (19th August 2018)
- Main Title:
- Synthesis of N−H Bearing Imidazolidinones and Dihydroimidazolones Using Aza‐Heck Cyclizations
- Authors:
- Xu, Feiyang
Shuler, Scott A.
Watson, Donald A. - Abstract:
- Abstract: The synthesis of unsaturated, unprotected imidazolidinones via an aza‐Heck reaction is described. This palladium‐catalyzed process allows for the cyclization of N ‐phenoxy ureas onto pendant alkenes. The reaction has broad functional group tolerance, can be applied to complex ring topologies, and can be used to directly prepare mono‐ and bis‐unprotected imidazolidinones. By addition of Bu4 NI, dihydroimidazolones can be accessed from the same starting materials. Improved conditions for preparing unsaturated, unprotected lactams are also reported.
- Is Part Of:
- Angewandte Chemie. Volume 130:Number 37(2018)
- Journal:
- Angewandte Chemie
- Issue:
- Volume 130:Number 37(2018)
- Issue Display:
- Volume 130, Issue 37 (2018)
- Year:
- 2018
- Volume:
- 130
- Issue:
- 37
- Issue Sort Value:
- 2018-0130-0037-0000
- Page Start:
- 12257
- Page End:
- 12261
- Publication Date:
- 2018-08-19
- Subjects:
- Aza-Heck-Reaktionen -- Dihydroimidazolone -- Homogene Katalyse -- Imidazolidinone -- Palladium
Chemistry -- Periodicals
540 - Journal URLs:
- http://onlinelibrary.wiley.com/ ↗
- DOI:
- 10.1002/ange.201806295 ↗
- Languages:
- English
- ISSNs:
- 0044-8249
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 0902.000000
British Library DSC - BLDSS-3PM
British Library HMNTS - ELD Digital store - Ingest File:
- 12301.xml