Cutaneous malignant melanoma of the oral cavity following skin graft reconstruction: Case report. Issue 2 (7th December 2018)

• Record Type: Journal Article
• Authors: Mayo, Zachary; Seyedin, Steven; Marquardt, Michael; Mohiuddin, Imran; Milhem, Mohammed; Liu, Vincent; Pagedar, Nitin; Anderson, Carryn
• Is Part Of: Head & neck. Volume 41:Issue 2(2019)
• Page Start: E26
• Page End: E29
• Publication Date: 2018-12-07
• Subjects: cutaneous melanoma -- free‐flap reconstruction -- graft reconstruction -- oral cavity -- recipient site; Head -- Diseases -- Periodicals; Neck -- Diseases -- Periodicals; Head -- Periodicals; Neck -- Periodicals; Face -- Periodicals; 617.51059
• DOI: 10.1002/hed.25417
• Languages: English
• ISSNs: 1043-3074

Abstract

Abstract: Background: Malignant melanomas on skin graft recipient sites are rare, with few cases reported in the literature. Methods: We present a case report of a patient with recurrent cutaneous melanoma in the grafted anterolateral thigh flap of the tongue. Results: A patient underwent hemiglossectomy with free flap reconstruction for squamous cell carcinoma of the tongue. Five years later the patient was seen with a 1‐cm nodule and surrounding erythroplakia at the recipient site of the graft. Analysis revealed cutaneous malignant melanoma. Patient then related a remote history of a suspected skin melanoma of the donor leg that had been treated with excision, with unknown histology. Conclusion: This may be the first reported case of a cutaneous malignant melanoma in the oral cavity following an anterolateral thigh free flap reconstruction, emphasizing the importance of obtaining a comprehensive history of skin cancers and closely inspecting the donor site prior to graft harvesting.