P441 Higher education, professional occupation and upper socio-economic status is associated with lower adherence to medications in patients with inflammatory bowel disease. (16th January 2018)

• Record Type: Journal Article
• Authors: Tomar, S K; Kedia, S; Singh, N; Upadhyay, A D; Bopanna, S; Yadav, D; Goyal, S; Jain, S; Makharia, G; Ahuja, V
• Is Part Of: Journal of Crohn's and colitis. Volume 12:Number 1(2018:Jan.)Supplement 1
• Page Start: S328
• Page End: S328
• Publication Date: 2018-01-16
• Subjects: Inflammatory bowel diseases -- Periodicals; 616.344005
• DOI: 10.1093/ecco-jcc/jjx180.568
• Languages: English
• ISSNs: 1873-9946

Abstract

Abstract: Background: The literature on medication adherence and its predictors in patients with inflammatory bowel disease (IBD) is heterogeneous. Present study was aimed to identify the rates, reasons, and predictors of non-adherence to medications in IBD. Methods: This prospective observational study included patients of IBD [ulcerative colitis (UC) and Crohn's disease (CD)] from November 2016–March 2017. The adherence was assessed with a questionnaire (interview based) which extracted information on the patients' sociodemographic profile, nutritional profile, smoking and drinking habits, disease profile, rates of medication adherence and reasons for non-adherence. All interviews were conducted by the same researcher in person. Results: Total of 266 patients (204 UC, 62 CD) were included [mean age: 38.47 ± 12.74 years, males: 142 (53.38%), mean disease duration: 6.35 ± 5.24 years]. Overall adherence rate was 82.3%, least for topical therapy (67.3%) and highest for steroids (95.9%). The reasons for non-adherence were forgetting dose (18.80%), unavailability of medications (13.16%), frequent drug dosing (4.14%), no effect of medication (3.01%), felt better (11.65%), side/adverse effects (6.79%), cost of treatment (6.02%) and lifelong treatment (3.38%). Patients' education ( p < 0.001), occupation ( p = 0.097), and socioeconomic status ( p = 0.021) had a negative association with adherence. Furthermore, patients in upper socio-economic strata with professional education and occupation were least adherent (47%), whereas patients belonging to the lower socioeconomic strata who were illiterate and unemployed had the highest adherence rates (100%). Conclusions: More than 80% patients were adherent to their medications; adherence was least for topical therapy. Higher education, occupation and upper socioeconomic status were negatively associated with adherence.